Translate

Sunday, August 14, 2016

Same Chemicals Causing Infertility Problems In Humans Now Found In Dogs


The same chemicals that disrupt sperm quality in humans are also being discovered in a range of commercially available dog foods--including brands specifically marketed for puppies. Sperm quality in dogs has fallen rapidly over the past three decades, a trend which could help explain the purported decline in human fertility.


Researchers at the University of Nottingham believe that the study could help explain the reported significant decline in human semen quality.

The work, published in Scientific Reports, highlights a potential link to environmental contaminants, after they were able to demonstrate that chemicals found in the sperm and testes of adult dogs--and in some commercially available pet foods--had a detrimental effect on sperm function at the concentrations detected.
"This is the first time that such a decline in male fertility has been reported in the dog and we believe this is due to environmental contaminants, some of which we have detected in dog food and in the sperm and testes of the animals themselves," said Richard Lea, reader in reproductive biology at the university’s School of Veterinary Medicine and Science, who led the research.
"While further research is needed to conclusively demonstrate a link, the dog may indeed be a sentinel for humans -- it shares the same environment, exhibits the same range of diseases, many with the same frequency, and responds in a similar way to therapies."

Poor studs
Lea and his team collected semen from between 42 and 97 stud dogs every year over 26 years at an assistance dogs breeding centre.
Semen samples were then analysed to assess the percentage of sperm that appeared normal and had the expected pattern of motility.
Sperm motility declined by 2.5 per cent per year between 1988 and 1998, and then at a rate of 1.2 per cent per year from 2002 to 2014.
The researchers also found that male pups fathered by the stud dogs with declining semen quality were more prone to cryptorchidism -- a condition in which the testes fail to correctly descend into the scrotum.
Lea said that genetic conditions were not to blame because the research was carried out over a relatively short period of time.
He said that the study "begs the question" whether a similar effect could be observed in human male fertility.
The purported decline in male fertility is a controversial subject in science with many criticising the variability of data in the studies.
However, Lea said that the University of Nottingham study provided a "unique set of reliable data from a controlled population" which was not affected by factors -- such as in laboratory methods, training of laboratory personnel or improved quality control over the years -- which could have caused variations to the results.
Over the past 70 years, studies have suggested a significant decline in human semen quality and a cluster of issues called "testicular dysgenesis syndrome" that affect male fertility and include increased incidence of testicular cancer, the birth defect hypospadias, and undescended testes.
However, declining human semen quality remains a controversial issue--many have criticized the variability of the data of the studies on the basis of changes in laboratory methods, training of laboratory personnel, and improved quality control over the years.
Sources: 
nottingham.ac.uk

No comments :

Post a Comment

Note: Only a member of this blog may post a comment.